Heart Failure with Preserved Ejection Fraction (HFpEF) – NEJM

Notes from NEJM Review Article:  Redfield MM. (2016), Heart Failure with Preserved Ejection Fraction Case:  73 yo woman seen for hospital f/u after admission for AF with RVR and pulm edema.  She c/o fatigue and DOE. Cr 1.4, eGFR 37, NT-proBNP 300.  Echo EF 70% with nl LV dimensions.  Elevated LA pressure and pulm arterial… Continue reading Heart Failure with Preserved Ejection Fraction (HFpEF) – NEJM

Alpha-blockers aid in passage of kidney stones (meta-analysis)

Meta-analysis: alpha blockers effective for kidney stonesClinical Question:In patients with kidney stones (ureteric calculi), is treatmentwith an alpha blocker effective in improving passage rate and decreasingpain?Bottom Line:Although a recent large study found no benefit to alpha blocker treatment (Lancet 2015;386:341-49), this meta-analysis of 55 studies found a benefit to using alpha blockers to increase the… Continue reading Alpha-blockers aid in passage of kidney stones (meta-analysis)

Asymptomatic Hypertensive Urgencies Can Be Managed Outpatient

Retrospective study of 59,000 patients presenting to outpatient setting with severe asymptomatic hypertension. No difference between those sent to the ED vs those managed as outpatients in: Major adverse CV events Uncontrolled HTN 6 mos later Only difference - those who went to the ED were hospitalized more often. Take-away:  Asymptomatic severe hypertension can be… Continue reading Asymptomatic Hypertensive Urgencies Can Be Managed Outpatient