Hypertension Treatment – NNTs

Based on new guideline from ACP and AAFP for the treatment of HTN in adults, published in Ann Intern Med 2017 Mar 21; 166:430.

For adults with SBP ≥ 160 mmHg, lowering the BP to < 150 mmHg, over a 5 year period:

  • All-cause mortality:   NNT = 61
  • Stroke:  NNT = 88.5
  • Adverse cardiac events:  NNT = 80

This guideline also concurs with the SPRINT trial that higher-risk patients (hx of CAD or hx of stroke/TIA) should be treated to a lower goal, but older patients (>60 yo) should be treated to <150 mmHg.

  • Pt with hx of TIA/stroke, treating to 130-140 mmHg to prevent stroke (but not adverse cardiac events nor all-cause mortality):  NNT = 33.1
  • The evidence quality for stroke risk reduction is low to moderate.

 

 

Advertisements

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s