Our case: 2015 renal transplant, nocardia diagnosed shortly after immunosuppressive therapy, possible hx of CMV.
Common infections: URI and UTI – are still common in the immunosuppressed. Common things are common.
- Viral: CMV, JC, HBV, HCV, VZV, EBV, HSV
- Bacterial: PCP, Listeria, Nocardia
- Fungal: Aspergillus, TB
Early Post-Transplantation: Immediately post-op to 1 month
- Typical 5Ws: water, wound, wonder drugs, wind…
- Opportunistic infections less common
1-6 Months Post-Transplantation: 1-6 mos
- Peak incidence of opportunistic infections
- Beware of CMV! (increases bacterial and fungal infx risk)
Late Post-Transplant: > 6 mos
- Decreased rate of opportunistic infections
- Chronic infections (e.g., CMV) in 10-15%