Metformin as Effective as Insulin for GDM

Metformin appears to be at least as effective as insulin for treatment of gestational diabetes mellitus

Clinical Question:
What are the short-term and long-term risks and benefits of metformin therapy compared with insulin therapy for glucose disorders in pregnancy?

Bottom Line:
The results of this systematic review and meta-analysis show that metformin is at least as effective as insulin in the management of gestational diabetes and type 2 diabetes during pregnancy. Most women would certainly rather take a pill than receive daily injections. (LOE = 1a-)

Reference:
Butalia S, Gutierrez L, Lodha A, Aitken E, Zakariasen A, Donovan L. Short- and long-term outcomes of metformin compared with insulin alone in pregnancy: A systematic review and meta-analysis. Diabetic Med 2017;34(1):27-36.

Advertisements

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s