Low-Dose Aspirin for Colorectal Cancer Prevention

Ann Intern Med 2015 Sep 1; 163:347
Case-control study of population registry from Denmark
n = 10,280 with first-time CRC with 102,800 controls
Continuous use of low-dose ASA (75-100mg) for > 5 years associated with 27% lower risk of CRC
Long-term use of non-ASA NSAIDs associated with 36% lower risk
Irregular use had no benefit
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