Intensive Blood Pressure Treatment a Mixed Bag of Outcomes

Meta-analysis: intensive BP control decreases major CV events and stroke,
but not MI, CHF, or mortality

Clinical Question:
Does intensive lowering of blood pressure improve the lives of patients with hypertension?

Bottom Line:
Patients with hypertension who are treated intensively are less likely to have major cardiovascular events, stroke, or progression of albuminuria or retinopathy than those treated less intensively, but intensive lowering had no meaningful effect on myocardial infarctions, heart failure, or mortality. (LOE = 1a)

Xie X, Atkins E, Lv
J, et al. Effects of intensive blood pressure lowering on cardiovascular and renal outcomes: updated systematic review and meta-analysis. Lancet 2016;387(10017):435-443.


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