Abnormal Transaminases (LFTs) – Differential Diagnosis

TOXIC
EtOH and APAP most common
Consider herbals, mushroom toxicity
IMMUNE
Autoimmune hepatitis
Primary biliary cirrhosis
Polymyositis
INFECTION
Viral hepatitis
OBSTRUCTIVE
– more biliary obstructive pattern (TBili, AlkPhos)
ISCHEMIC
Blood loss, Budd-Chiari, shock…
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