Metformin for Impaired Glucose Tolerance (Prediabetes)

IFG, IGT, or A1C (5.7 to 6.4 percent)* Lifestyle modification (ie, 5 to 10 percent weight loss and moderate intensity physical activity ~30 min/day)
Individuals with IFG, IGT, or A1C 5.7 to 6.4 percent, especially for those: Lifestyle modification (as above) and/or metformin
<60 years of age
BMI ≥35 kg/m2
Women with prior gestational diabetes
IFG: impaired fasting glucose; IGT: impaired glucose tolerance; A1C: glycated hemoglobin; BMI: body mass index.
* Updated information from American Diabetes Association. Standards of medical care in diabetes—2013. Diabetes Care 2013; 36 Suppl 1:S11.
¶ Metformin 850 mg twice per day.

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