Wilson Disease – Pearls

Wilson’s disease

  • (-) ceruloplasmin does not rule out
  • Keyser-Fleischer rings absent in 50%
  • AST & ALT <1500
  • Normal or low alk phos for age (cofactor Zn displaced by Cu)
  • AST:ALT >2.2
  • AlkPhos : TotBili <4
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