Gabapentinoids not useful as adjunct pain management after knee
Are gabapentinoids useful in managing postoperative pain in patients undergoing total knee arthroplasty?
The gabapentinoids [gabapentin (Neurontin) and pregabalin (Lyrica)] are not significantly effective as an adjunct to pain management after total knee arthroplasty. (LOE = 1a-)
Strickland LH, Pandit HG. A meta-analysis on the use of gabapentinoids for
the treatment of acute postoperative pain following total knee
arthroplasty. J Bone Joint Surg Am 2016;98(16):1340-1350.